Application

Sleep disruptions significantly impact cognitive recovery and daily systemic health. SAFFR'ACTIV® is the first commercialized saffron extract scientifically proven in a published double-blind clinical trial to improve sleep quality using objective polysomnographic and validated questionnaire metrics in subjects with chronic primary sleep disorders.

Chronic psychological stress destabilizes the HPA axis and gut microbiota balance. GPE offers multi-action synergistic extracts: SAFFR'ACTIV® normalizes neurotransmitter recycling; PROBIOSTRESS®zen regulates the gut-brain axis; SCUTELL'UP® supports neuronal resilience; and CENTELLORY® preserves mental calm under acute pressure.

Urinary tract health requires bioactive compounds capable of inhibiting bacterial adherence. CRAN'BEY® contains standardized A-type proanthocyanidins (PACs) derived from premium North American cranberry (*Vaccinium macrocarpon*), backed by clinical evidence for preventing uropathogenic *E. coli* adhesion.

Designed for age-related cognitive care and active mental performance, CENTELLORY® is a highly purified *Centella asiatica* extract. Rich in triterpenoid saponins, it supports microcirculation, promotes synaptic plasticity, and aids memory consolidation.

Standard caffeine triggers rapid blood plasma spikes followed by energy crashes. BEAN'ERGY® utilizes microencapsulation technology to ensure controlled, gradual release of natural caffeine, sustaining alertness and sharp executive focus over an extended period without jitters.

SAFFR'ACTIV® is the first commercial botanical extract clinically validated as an effective natural intervention for Attention Deficit/Hyperactivity Disorder (ADHD). Proven in a published clinical study at Hospital Universitario Puerta de Hierro Majadahonda, it enhances attention span and hyperactive control in pediatric and adolescent populations.